Skip to content
Eco Hormone Balance iconEco Hormone Balance

Natural Hormonal Wellness for Women

If you're feeling tired or off-balance, try natural methods to balance your hormones. Explore supplements like natural estrogen pills and herbs for hormonal balance, regulating hormones naturally, and achieving holistic hormone balance.

Guides to Get You Started

Step-by-step resources to understand inositol and hormonal balance.

Explore guides →

Inositol Reviews

Head-to-head ratings, pros and cons, and labeling checks.

Read the reviews →

What is Inositol & How Does It Work?

Inositol is a natural carbohydrate that acts as a key messenger for hormonal signals, including insulin. For supporting hormonal balance, research points to a specific combination as the most effective: Myo-inositol (MI) and D-Chiro-inositol (DCI).

When taken as a supplement, this blend helps restore the body's optimal 40:1 ratio. This is crucial for improving insulin sensitivity and regulating hormonal pathways, especially for managing conditions like PCOS. Many formulas also include folic acid or vitamin D3 for added support.

Discover the Complete Inositol Guide
Illustration of inositol benefits

Best Myo-Inositol And D-Chiro Inositol Supplements for 2025

We've reviewed the top-rated inositol blends with the optimal 40:1 ratio. Compare supplements with added vitamin D3, folic acid, and chromium to find the right one for you.

Studio flat-lay of Ovasitol 40:1 inositol powder with a generic label on a neutral background, no trademarks.

Theralogix Ovasitol Inositol Powder

Ovasitol Inositol Powder from Theralogix (40:1) for hormonal support, fertility, and ovarian function in women with PCOS. 100% pure, vegan, NSF-certified. Two versions: packets or jar.

Wholesome Story Myo & D-Chiro Inositol 40:1 bottle with capsules on a sunlit kitchen counter.

Wholesome Story Myo-Inositol & D-Chiro Inositol (40:1)

Inositol blend (40:1 ratio) supplement from Wholesome Story for hormonal support and fertility in women with PCOS. Vegan formula, GMP-certified. Results vary; consult a doctor.

See All Inositol Supplement Reviews

Why Choose a 40:1 Inositol Blend?

Our recommended supplements are based on scientific evidence to provide the most effective support for hormonal wellness.

  • Optimal 40:1 Ratio

    Supports the crucial ratio of Myo-inositol to D-Chiro-inositol for hormonal balance. Learn why it matters.

  • Cycle & Fertility Support

    Aids in regulating menstrual cycles and promoting ovulation, particularly for women with PCOS.

  • Metabolic Health

    Improves insulin sensitivity, a key factor in managing PCOS symptoms and overall metabolic function.

  • Comprehensive Formulas

    Often includes synergistic ingredients like folic acid & vitamin D3 for enhanced support.

  • Purity You Can Trust

    Our top picks are third-party tested for purity and potency, ensuring a high-quality, safe supplement.

  • New to Inositol?

    Start with our complete beginner's guide to understand the basics.

Trusted Brands We've Reviewed

We only feature brands that meet our high standards for quality, transparency, and effectiveness.

Wholesome Story logo
Theralogix logo
Explore All Reviewed Brands

Learn More About Inositol

Our evidence-based guides to help you understand the benefits and science behind Myo & D-Chiro Inositol.

Best diet for PCOS: low-carb and alternatives

Nutrition & Supplements

Best Diet for PCOS: Low-Carb and Alternatives

The best PCOS diets, from low-carb to low-GI, Mediterranean, and DASH, with evidence on insulin, weight, and cycles.

A split-screen image showing a bright, sunny morning window on the left and a calm, starry night sky on the right, with a stylized inositol molecule in the center, representing the choice of when to take it.

Nutrition & Supplements

Best Time to Take Inositol: Morning or Night?

Split 2 g myo-inositol twice daily and take each dose before meals. See when morning or night fits your goals and how to dose safely.

Conceptual image showing a bottle of Inositol supplement next to a stylized Vitamin B-complex icon with a question mark, illustrating the difference between them.

Nutrition & Supplements

Is Inositol a Vitamin? Differences with B8

Is inositol a vitamin? This guide clarifies why it was once called Vitamin B8 and explains the key differences from true B-vitamins, backed by scientific insights.

View all guides

Frequently Asked Questions

Is this medical advice?

No. Our content is for educational, evidence-informed purposes only. Always consult a licensed professional for personal care.

Do you sell supplements?

We do not sell products directly. We may recommend options and will always disclose affiliate links when present.

Who writes and reviews your articles?

Our in-house editorial team leads all content creation and review. Please see our Editorial Policy for our standards.